Clinical Uncertainties, Health Service Challenges, and Ethical Complexities of HIV "Test-and-Treat": A Systematic Review.

Abstract

Despite the HIV "test-and-treat" strategy’s promise, questions about its clinical rationale, operational feasibility, and ethical appropriateness have led to vigorous debate in the global HIV community. We performed a systematic review of the literature published between January 2009 and May 2012 using PubMed, SCOPUS, Global Health, Web of Science, BIOSIS, Cochrane CENTRAL, EBSCO Africa-Wide Information, and EBSCO CINAHL Plus databases to summarize clinical uncertainties, health service challenges, and ethical complexities that may affect the test-and-treat strategy’s success. A thoughtful approach to research and implementation to address clinical and health service questions and meaningful community engagement regarding ethical complexities may bring us closer to safe, feasible, and effective test-and-treat implementation.

BibTeX

@article{Kulkarni2013,
  author = {Kulkarni, S. P. and Shah, K. R. and Sarma, K. V. and Mahajan, A. P.},
  doi = {10.2105/AJPH.2013.301273},
  issn = {1541-0048},
  journal = {American Journal of Public Health},
  month = apr,
  pmid = {23597344},
  title = {{Clinical Uncertainties, Health Service Challenges, and Ethical Complexities of HIV "Test-and-Treat": A Systematic Review.}},
  url = {http://www.ncbi.nlm.nih.gov/pubmed/23597344},
  year = {2013},
}

copy bibtex